MYTH: Once broad-spectrum antibiotics are initiated for sepsis, they should rem…
MYTH: Once broad-spectrum antibiotics are initiated for sepsis, they should remain unchanged throughout treatment.
FACT: Antimicrobial therapy should be reassessed as microbiology results, infection source and the patient's clinical course become clearer. De-escalation or other treatment adjustments can help support appropriate antimicrobial use while maintaining effective infection management.
Clinical pearl: Timely initial treatment and ongoing reassessment are complementary parts of sepsis care.
Reference: https://sccm.org/survivingsepsiscampaign/guidelines-and-resources/surviving-sepsis-campaign-adult-guidelines?
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sccm.org
Surviving Sepsis Campaign Adult Guidelines
These recommendations reinforce the core pillars of sepsis care while adding more detail, clarity, and nuance to guide real-world clinical decisions.