Obesity is a chronic disease that requires long-term manage…

Obesity is a chronic disease that requires long-term management, not just short-term treatment.

GLP-1 receptor agonists have changed the way we treat obesity, helping many people achieve meaningful weight loss. However, one of the biggest challenges is maintaining those results after treatment is stopped.

Meta-regression analyses show that within one year of discontinuing GLP-1RA therapy, individuals regain approximately 60% of the weight they lost during treatment.

Source:

Budini B, Luo S, Tam M et al. Trajectory of weight regain after cessation of GLP-1 receptor agonists: a systematic review and nonlinear meta-regression. EClinicalMedicine. 2026 Mar 4:93:103796.  doi: 10.1016/j.eclinm.2026.103796. eCollection 2026 Mar.